Join Buck Joffrey, M.D. and Nikki Leigh as they explore the revolutionary world of full-body MRIs with Dr. Sefi, a radiologist at Prenuvo. These advanced scans can detect over 500 conditions—ranging from cancer to aneurysms—long before symptoms appear. Discover how cutting-edge technology drives a transformative shift from reactive to proactive medicine, giving you the power to take charge of your health. Packed with expert insights, personal stories, and actionable advice, this episode reveals why prevention is the key to living a longer, healthier life. 

Discover how cutting-edge AI is reshaping the battle against cancer. Buck and Nikki dive deep into the revolutionary Galleri test with Dr. Joshua Hoffman, which screens for over 50 types of cancer using AI-driven blood analysis. Learn how this test identifies early-stage cancers, why it's a game-changer in preventative medicine, and its potential to save thousands of lives annually. Don't miss this insightful discussion on harnessing technology for longevity and health optimization.

Dive deep into the art of fasting for longevity with Dr. Valter Longo, a renowned gerontologist and director of USC’s Longevity Institute.

In this episode, Nikki and Buck explore groundbreaking insights into fasting, nutrition, and their impact on metabolic health and lifespan.

Learn why 12-hour eating windows might outlast trendy 8-hour fasts for long-term health, and how the Fasting Mimicking Diet offers a game-changing alternative to traditional fasting.

Plus, discover the surprising truths about protein, aging, and how cycles of nutrition can reset your biological clock.

This episode is packed with actionable tips for those striving to balance health and longevity. Whether you're a fasting novice or a seasoned longevity enthusiast, tune in to unravel the myths and science behind fasting.

In this episode of Longevity Roadmap, Dr. Robert Lufkin, New York Times bestselling author and renowned UCLA professor, uncovers powerful insights on how lifestyle choices can transform health, reverse chronic diseases, and enhance longevity. Tune in as Dr. Lufkin joins hosts Nikki Leigh and Buck Joffrey to debunk diet myths, reveal the truth about metabolic health, and explore actionable ways to reduce inflammation, improve sleep, and increase energy.

Whether you're looking to break free from modern health misconceptions, understand the impact of diet on your healthspan, or find practical steps to support long-term wellness, this episode is packed with science-backed strategies and relatable insights. Discover how simple lifestyle shifts can be more effective than pills, as Dr. Lufkin explains the real secrets to living a longer, healthier life.

A wonderful interview on exercise and the runner's high with Nike Run Club Head Coach Bec Wilcock. The app has over 100 million users worldwide.

An amazing interview with Aubrey de Grey, a founding father of the longevity movement—the man who coined the phrase 'Longevity Escape Velocity.'

Tears and laughter in this compelling episode about the benefits of Ketamine for neuroplasticity to treat depression, trauma, or a lack of ambition.

In this eye-opening episode, Nikki is midway through a week of Ayahuasca therapy and chats with Buck and Dr. Jeff Mcnairy of the Rythmia Retreat Center, about this amazing PTSD and trauma therapy.

Buck and Nikki dive into women's sexual health and erectile dysfunction and learn why microdosing cialis can be a real longevity hack.

Buck and Nikki sit down with Dan Buettner, creator of the Netflix series Live to 100: Secrets of the Blue Zones, to explore the wisdom of the world's longest-lived populations. They dive into the lifestyle, diet, and environmental factors that contribute to longevity, and how you can engineer these principles to extend your healthy lifespan.

Buck and Nikki tackle one of the most contentious and polarizing areas of longevity, diet with Bio Layne founder Dr. Layne Norton.

In this episode, Buck and Nikki sit down with renowned psychiatrist and brain disorder specialist, Dr. Daniel Amen, founder of Amen Clinics, to discuss groundbreaking brain imaging techniques like SPECT scans. Dr. Amen shares insights on diagnosing mental health issues through brain mapping and the role of brain health in overall longevity.

An introduction to Longevity Junky, our hosts Dr. Buck Joffrey and Nikki Leigh, and an interview about the rapid and miraculous progress being made in biological age reversal with Dr. Joel Rothman.